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Introduction Over the years, advances in neurology and research have simplified the way psychologists, psychiatrists, and others diagnosis and treat mental health problems.
In over one hundred years of mental health treatment, the symptoms and behaviors associated with certain mental health conditions have remained the same.
Hyperactive children Attention-Deficit Hyperactivity Disorder or ADHD still exhibit uncontrollable restlessness.
When patients first began reclining on the couches of psychoanalytic psychiatrists, the depressed folks talked about their past.
This led the founders of psychology and psychiatry to believe that issues that began in childhood caused many mental health problems.
But questions were still not answered.
Why would a bad relationship with your mother create the appetite loss found in depression, especially when eating problems only started several months prior to the session?
By what strange mechanism would a childhood issue create an auditory hallucination, often years after the reported traumatic event?
It became clear that many mental health problems also had a physical component that involved changes in concentration, sleep, appetite, speech pattern, energy level, perceptions hallucinationsand motivation.
The brain consists of billions of neurons or cells that must communicate with each other.
The communication between neurons maintains all body functions, informs us when a fly lands on our hand, or when we have pain.
Neurotransmitters are chemical substances that control and create signals in the brain both between and within neurons.
Without neurotransmitters, there would be no communication between neurons.
Serotonin, a neurotransmitter, was found to be related to body temperature and the onset of sleep.
Research also identified Serotonin as related to depression and later to a variety of mental health conditions such as anorexia and obsessive-compulsive disorder.
As research in neurotransmitters continued, studies between neurotransmitters and mental conditions revealed a strong connection between amounts of certain neurotransmitters in the brain and the presence of specific psychiatric conditions.
Using an everyday example, our automobile operates by using a variety of fluids such as engine oil, transmission fluid, brake fluid, and coolant anti-freeze.
Every automobile has a way to measure the levels or amounts of each of these needed liquids such as the dipstick for oil and transmission fluid and marked indicators for anti-freeze and brake-fluid levels.
Using our dipstick to measure engine oil, for an example, we can find our engine to be found one, two, or even three quarts low.
After a recent oil change, the dipstick may also tell us that we have excessive oil in the engine.
Neurological research has identified over fifty 50 neurotransmitters in the brain.
Research also tells us that several neurotransmitters are related to mental health problems — Dopamine, Serotonin, Norepinephrine, and GABA Gamma Aminobutyric Acid.
Too much or too little of these neurotransmitters are now felt to continue reading psychiatric conditions such as schizophrenia, depression, bi-polar disorder, obsessive-compulsive disorder, and ADHD.
There are advanced imaging techniques such as Positron Emission Tomography PET Scans that are being utilized in research and in the development of medications that directly influence changes in specific neurotransmitters.
This is perhaps best illustrated in individuals with depressed mood.
The mental health professional is often required to separate those who would benefit from counseling and those who may require counseling and an antidepressant medication.
For example, situational depression often produces sad expressions, worry, pessimistic attitude and other features but does not create prolonged changes in the physical symptoms such as changes in sexual interest, appetite, or sleep.
The technical aspects of neurotransmitter levels, the psychiatric symptoms they produce, and how medications have been developed to raise or lower online gambling and betting mintel brain levels of these neurotransmitters can be very complicated.
Medical patients with high blood pressure, high blood sugar, or high cholesterol are informed that their body chemistry is too high, or in some cases, too low and must be corrected with medication.
This simple and commonly used explanation recognizes that the condition is a medical problem and that it can be treated with medication.
Despite having these resources, there are times when coping with our experiences and life events changes our neurotransmitter status.
Like an overheated automobile, we begin to have difficulty operating properly.
Mostly commonly, we will experience depression, anxiety, or stress reactions.
As our neurotransmitters change, they bring with them additional symptoms, behaviors, and sensations that add to our on-going difficulties.
Recognizing these changes is an important part of treatment and returning your life to normal and reducing our stress.
This discussion is offered to explain how the neurotransmitter system in the brain can create psychiatric conditions and mental health problems.
It is hoped the discussion will provide information that will be of value to those who suspect their neurotransmitter system is creating problems.
The following is a discussion of neurotransmitters and current thoughts about how these neurochemicals are involved in psychiatric illness.
Four neurotransmitters, out of over fifty, are well researched and known to be related to psychiatric conditions.
Dopamine strongly influences both motor and thinking areas of the brain.
One type of Dopamine works in the brain movement and motor system.
Low levels of Dopamine make concentration and focus very difficult with low levels also associated with Attention-Deficit Hyperactivity Disorder ADHD.
Mild elevations in Dopamine are associated with addictions.
Nicotine, cocaine, and other substances produce a feeling of excited euphoria by increasing Dopamine levels in the brain.
As Dopamine levels increase above the normal range, our ability to focus increases to the point of being paranoid.
Mild elevations make the environment overly stimulating and excited.
Moderately high Dopamine levels make us on-guard, suspicious, and prone to misinterpret experiences in the environment.
People observed talking across the street are now talking about us.
As Dopamine increases, it can become so intense that we feel the radio, television, and newspaper contain secret messages directed at us from Hollywood or elsewhere.
Planes flying overhead are snapping pictures of us and motorists talking on cellular phones are calling in a report on us.
Our mind speed increases and races in an attempt to add all we see into our life.
In an attempt to make sense, we may become extremely religious, paranoid, or feel we are a very important person.
Increased Dopamine also increases the perception of our senses, as though turning up the volume in all our senses — hearing, vision, taste, smell, and touch.
As Dopamine levels increase, the noises we heard loudly suddenly become auditory hallucinations.
Our inner thoughts are now being heard outside our body.
Hallucinations experiencing something that is not truly there in reality will soon develop in all our senses.
We may begin seeing faces in clouds, carpets, or patterns.
We may sense the touch of spirits or movements inside our body.
We may experience unusual smells or tastes.
High levels of Dopamine in the brain often cause us to lose our contact with reality.
As though living in a science-fiction movie, we begin to develop unusual if not bizarre ideas about what is happening to us.
With our paranoia, we may experience delusions false beliefs of persecution or may think we have super powers delusions of grandiosity and can predict the future or read minds.
High levels of Dopamine are found in Schizophrenia, drug intoxication, and other psychotic conditions where the ability to distinguish the inner world from the real world is impaired.
Low-Dopamine disorders are treated with medications that increase Dopamine in the brain.
Amphetamines and medications with similar action actually slow down the hyperactive ADHD children by increasing Dopamine — boasting their level into the normal range, allowing them to now focus and attend.
Thus, medications used in the treatment of addictions actually block or lower Dopamine production.
If a medication blocks dopamine, it also blocks the effects of the addicted substance as well as blocking the craving sensation.
The medication to help smokers, Zyban, is actually the antidepressant Wellbutrin that is known to block Dopamine.
Moderate to high levels of Dopamine, associated with severe psychiatric conditions such as Paranoia and Schizophrenia, are treated with medications that block or lower Dopamine in the brain.
These medications, called antipsychotics, have been available for many years.
Newer medications have fewer side effects in motor areas, as they are able to specifically target one type of Dopamine.
Dopamine levels typically change very slowly.
A typical high school or college student may develop a sense of being on-edge or unusual feelings, gradually becoming suspicious and feeling alienated, moving into auditory hallucinations, and finally click here bizarre false beliefs delusions of persecution or exaggerated self-importance over the next several years.
Stress can often rapidly increase Dopamine, but it still rarely happens overnight.
The prolonged use of amphetamines speed or steroids can produce a loss of reality and sudden paranoia.
The sudden presence of psychosis hallucinations, delusions, paranoia, etc.
Serotonin is a major regulator and is involved in bodily processes such as sleep, libido sexual interestbody temperature, and other areas.
Perhaps the best way to think of Serotonin is again with an automobile example.
Most automobiles in the United States are made to cruise at 70 miles per hour, perfect for interstate highways and that summer vacation.
check this out we place that same automobile gambling and manic depression a racetrack and drive day-after-day at 130 mph, two things would happen.
Parts would fail and we would run the engine so hot as to evaporate or burnout the oil.
Like a normal automobile on a race track, when we find ourselves living in a high stress situation for a prolonged period of time, we use more Serotonin than is normally replaced.
Imagine a list of your pressures, responsibilities, difficulties and environmental issues difficult job, bad marriage, poor housing, rough neighborhood, etc.
Prolonged exposure to such a high level of stress gradually lowers our Serotonin level.
An automobile can be one, two or three quarts low in oil.
Using the automobile as an example, imagine that brain Serotonin can have similar stages, being low one quart lowclick at this page low two quarts lowand severely low three quarts low.
The less Serotonin available in the brain, the more severe our depression and related symptoms.
When Serotonin is low, we experience problems with concentration and attention.
We become scatterbrained and poorly organized.
Routine responsibilities now seem overwhelming.
It takes longer to do things because of poor planning.
We lose our car keys and put odd things in the refrigerator.
We call people and forget why we called or go to the grocery and forget what we needed.
We tell people the same thing two or three times.
As stress continues and our Serotonin level continues to drop, we become more depressed.
When Serotonin is moderately low, we have the following symptoms and behaviors: · Chronic fatigue.
Despite sleeping extra hours and naps, we remain tired.
· Appetite disturbance is present, usually in two types.
We experience a loss of appetite and subsequent weight loss or a craving for sweets and carbohydrates when the brain is trying to make more Serotonin.
· Total loss of sexual interest is present.
In fact, there is loss of interest in everything, including those activities and interests that have been enjoyed in the past.
· Emotional sadness and frequent crying spells are common.
· Self-esteem and self-confidence are low.
· Loss of personality — a sense that our sense of humor has left and our personality has changed.
· We begin to take everything very personally.
Comments, glances, and situations are viewed personally and negatively.
If someone speaks to you, it irritates you.
You talk less, smile less, and sit for hours without gambling and manic depression anyone.
· Your behavior becomes odd.
Family members may find you sitting in the dark in the kitchen at 4:00 am.
Individuals can live many years moderately depressed.
They develop compensations for the sleep and other symptoms, using sleeping medication or alcohol to get some sleep.
Very low levels of Serotonin typically bring people to the attention of their family physician, their employer, or other sources of help.
Severe Serotonin loss produces symptoms that are difficult to ignore.
When Serotonin is severely low, you will experience some if not all of the following: · Thinking speed will increase.
You will have difficulty controlling your own thoughts.
Crying outbursts will surface, suddenly crying without much warning.
Behavioral outbursts will also surface.
If you break the gambling and manic depression in a pencil, you throw the pencil across the room.
Temper tantrums may surface.
You may storm out of offices or public places.
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The brain will suggest packing up your personal effects and leaving the family and community.
· Memory torture will begin.
Your brain, thinking at 100 miles an hour, will search your memories for your most traumatic or unpleasant experiences.
You will suddenly become preoccupied with horrible experiences that may have happened ten, twenty, or even thirty years ago.
New mothers may have thoughts about smothering their infants.
Thoughts of harming or killing others may appear.
· With Serotonin a major bodily regulator, when Serotonin is this low your body becomes unregulated.
A bruise is leukemia.
About 70 percent of jobs are lost at this time as depressed individuals gradually fade away from their life.
Most extramarital affairs occur at this time.
You may develop rituals involving safety and counting.
· Whatever normal personality traits, quirks, or attitudes you have, they will suddenly be increased three-fold.
A perfectionist will suddenly become anxiously overwhelmed by the messiness of their environment or distraught over leaves that fall each minute to land on the lawn.
Penny-pinchers will suddenly become preoccupied with the electric and water consumption in the home.
Already moderately low in Serotonin, an animal bite or scratch may make you suddenly preoccupied with rabies.
A media story about the harmful effects of radiation may make you remember a teenage tour of the local nuclear power plant — suddenly feeling all your symptoms are now the result of exposure to radiation.
Everyone with severely low Serotonin is told the same thing.
At that point, you develop suicidal thoughts.
Clinical Depression is perhaps the most common mental health problem encountered in practice.
One in four adults will experience clinical depression within their lifetime.
Treatment for depression, as might be expected, involves increasing levels of Serotonin in the brain.
Since the mid-eighties, medications have been available that attempt to specifically target and increase Serotonin.
Like all neurotransmitters, we can have too much Serotonin.
Likely to occur by accident by combining two Serotonin-increasing medications or substances, Serotonin Syndrome SS produces violent trembling, profuse sweating, insomnia, nausea, teeth chattering, chilling, shivering, aggressiveness, over-confidence, agitation, and malignant hyperthermia.
Emergency medical treatment is required, utilizing medications that neutralize or block the action of Serotonin as the treatment for Serotonin Syndrome SS.
Like Dopamine, Serotonin can be accidentally increased or decreased by substances.
One method of birth control is known to produce severe depression as it lowers Serotonin levels.
A specific medication for acne has also been linked with depression and suicidal ideation.
For this reason, always inform your physicians if you are taking any medication for depression.
Also avoid combining antidepressants with any herbal substances reported to be of help in Depression such as St.
This neurotransmitter is similar to adrenaline and is felt to set threshold levels to stimulation and arousal.
Emotionally, anxiety and depression are related to norepinephrine levels in the brain, as this neurotransmitter seems to maintain the balance between agitation and depression.
Low levels of norepinephrine are associated with a loss of alertness, poor memory, and depression.
It is for this reason that medications for depression and ADHD often target both dopamine and norepinephrine in an attempt to restore both to normal level.
Mild elevations in our norepinephrine levels produce heightened arousal, something known to be produced by stimulants.
This increased sense of arousal is pleasurable, linking these substances to their potential for addiction.
Moderately high levels of norepinephrine create a sense of arousal that becomes uncomfortable.
Almost all anxiety disorders involve norepinephrine elevations.
Severe and sudden increases in norepinephrine are associated with panic attacks.
This animal response was activated in early man when a bear showed up at his cave or when faced with a tiger in the woods.
In modern times, imagine your reaction if while calmly watching television, someone or something started trying to knock your front door in to attack you.
Known now as panic attacks, they can surface at the grocery, at church, or when you least expect it.
As norepinephrine is a fast-acting neurotransmitter, the panic attack may last less than ten minutes feels like hours however!
Panic attacks are strong physical and chemical events and include the following symptoms: · Palpitations, pounding heart or rapid heart rate · Sweating and body temperature changes · Trembling or shaking · Shortness of breath of smothering sensations · Choking sensations · Chest pain and discomfort · Click or stomach distress · Dizziness, lightheadedness, or feeling faint · Sense of unreality, as though you are outside yourself · Fear of losing control or going crazy · Fear of dying · Numbness and tingling throughout the body · Chills and hot flushes If we think about the automobile example, a panic attack is the equivalent of your dashboard warning lights coming on — your stress level is too high.
Panic attacks, or surges of norepinephrine, can also occur by accident as when created by the use of certain medications.
The medications for certain medical conditions can cause a panic attack or increase our level of anxiety.
Medications often used for asthma, for example, can create anxiety or panic attacks.
Treating low or elevated levels of norepinephrine in the brain involve different approaches.
Low levels of norepinephrine are often treated using newer antidepressants.
Treatment for high levels of norepinephrine, as found in anxiety and panic disorders, involves decreasing neurotransmitter levels directly or using medications which increase another neurotransmitter that inhibits or decreases the action of norepinephrine.
One of those inhibiting neurotransmitters is GABA, also known as Gamma-Aminobutyric Acid.
GABA: Mania and Seizures to Relaxation and Impulse Control Gamma-Aminobutyric Acid GABA is a neurotransmitter that is inhibitory, that is, it decreases the ability of other neurotransmitters to work.
GABA is involved in our level of excitability.
Rather than encouraging communication between cells such as Dopamine, Serotonin or Norepinephrine - GABA reduces, discourages, and blocks communication.
This neurotransmitter is important in brain areas involving emotion and anxiety.
When GABA is in the normal range in the brain, we are not overly aroused or anxious.
At the same time, we have appropriate reactions to situations in our environment.
GABA is the communication speed controller, making sure all brain communications are operating at the right speed and with the correct intensity.
Too little GABA in the brain, the communication becomes out of control, overstimulated, and chemically unstable.
Too much GABA and we are overly relaxed and sedated, often to the point that normal reactions are impaired.
Low levels of GABA are associated with Bipolar Disorder, Mania.
With GABA levels read more average, the brain is too stimulated.
We begin talking rapidly, staying up for days at a time, and develop wild and grandiose ideas.
We may feel so good that we think we are a heavenly spirit, an intellectual genius, or possessing extraordinary powers.
Low levels of GABA are also associated with problems of poor impulse control, including clinical conditions such as gambling, temper tantrums, and stealing.
When GABA is low in the brain, impulsive behaviors are not inhibited stopped by logical or reasonable thinking.
Low levels of GABA are also associated with epilepsy or seizure disorders.
If we imagine a seizure as a type of electrical storm, the seizure begins at one location in the brain then rushes across and through the brain like a sudden storm.
Low levels of GABA make it easy for the brain to develop seizures which is why seizures are part of the withdrawal syndrome for many substances that work with GABA such as alcohol and tranquilizers benzodiazepines — Xanax, Ativan, Gambling and manic depression, Valium, etc.
Substances that artificially maintain a high level of GABA, when stopped, create a dramatic drop in GABA levels, thus creating the risk for withdrawal seizures due to the chemical instability that is created.
High levels of GABA produce more control, relaxation, and even sedation.
Alcohol works by increasing GABA levels, which is why all body systems are relaxed at first — then sedated to the point of slurred speech, unsteady gait, and foggy thinking.
Alcohol withdrawal, or the sudden severe drop of high GABA levels, produce a low GABA level and the possibility of seizures.
Withdrawal from benzodiazepines is known to follow the same pattern.
Taking forty milligrams of Valium for two years, suddenly stopping all medication, will likely produce a seizure.
Medications for anxiety create relaxation and a decrease in anxiety by increasing GABA levels in the brain.
Alcoholic beverages work in the same manner; the alcohol increasing GABA levels to produce mild euphoria, loss of social anxiety, and other symptoms of intoxication.
Medications for seizures, impulse control problems, and Bipolar Disorder, Mania all work by increasing the GABA levels without accompanying euphoria.
Lithium and anti-seizure medications all increase GABA into the normal range, thus lowering the possibility of seizures and producing brain chemical stability.
As GABA is the neurotransmitter gambling and manic depression, changes in GABA can influence all neurotransmitters but especially norepinephrine.
Mental health professionals use psychological testing, interviews, questionnaires, gambling and manic depression patient history to determine first, if a change in the neurotransmitter system is present, then second, what neurotransmitters are involved.
A proper clinical diagnosis then leads to proper medication treatment.
Much like a physician may prescribe a medication to lower your cholesterol or increase another body chemical, mental health professionals are concerned with returning your neurotransmitter levels to normal.
Medications for mental health conditions work in several ways: gambling and manic depression Some imitate the neurotransmitter, triggering a response as though the original neurotransmitter were present · Some block the neurotransmitter from being absorbed by the surrounding neurons, known as blocking the reuptake.
Cocaine does this to Norepinephrine and Dopamine while MDMA Ecstasy — a club drug does this to Serotonin.
· Some increase neurotransmitters known to slowdown or reduce the production of other neurotransmitters.
These changes can then create mental health problems.
It is the hope of mental health professionals that the public can understand the medical and neurochemical nature of various emotional and psychiatric conditions, thus eliminating the stigma often associated with treatment.
Modern treatment is very effective and can eliminate years of emotional suffering with very little in the way of intervention or treatment.
Mental health treatment is available in every county in the United States.
This article is presented as a public service by Joseph M.


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